学术成果

历年发表文章

研究领域与成果:
    
         从线粒体角度出,探索线粒体代谢变化的基本律和退特征;研究病理条件下线粒体损伤及其修复程中的关信号通路和调节分子;筛选发现改善线粒体功能、有效应对线粒体退从而改善和解相关疾病的养素或天然物。在国期刊共表SCI文190余篇, H因子62 (Google Scholar 2018.12.01)。邀在国内外各种学议发表演100 余次。 申请专利15(11), 主国内首部线粒体医学专著《线粒体医学与健康》,科学出版社2012年8月出版; 主持编写《人体线粒体功能障碍与重大疾病研究》丛书(共9卷)成功入选“十三五”国家重点出版规划图书 。连续五年(2014-2018)入选爱维尔高被引中国学者”榜 (生物化学,遗传学和分子生物学域)


 
 

近年发表的学术论文:

 

2019:

 

1.      Proinflammatory macrophages impair skeletal muscle differentiation in obesity through secretion of tumor necrosis factor‐α via sustained activation of p38 mitogen‐activated protein kinase.
      Wang X, Zhao D, Cui Y, Lu S, Gao D, Liu J.
     Journal of cellular physiology, 2019, 234(3): 2566-2580.
 
2.       Transmembrane protein 215 promotes angiogenesis by maintaining endothelial cell survival.
       Liu Y, Zheng Q, He G, Zhang M, Yan X, Yang Z, Zhang P, Wang L, Liu J, Liang L, Han H.
      Journal of Cellular Physiology, 2019, 234(6): 9525-9534.
 
3.       Regulation of DNA methylation and 2-OG/TET signaling by choline alleviated cardiac hypertrophy in spontaneously hypertensive rats .
      Liu L, He X, Zhao M, Yang S, Wang S, Yu X, Liu J, Zang W.
     Journal of molecular and cellular cardiology, 2019, 128: 26-37.
  
4.    Cornulin Is Induced in Psoriasis Lesions and Promotes Keratinocyte Proliferation via Phosphoinositide 3-Kinase/Akt  Pathways.
       Li C, Xiao L, Jia J, Li F, Wang X, Duan Q, Jing H, Yang P, Chen C, Wang Q, Liu J, Shao Y, Wang N, Zheng Y.
      Journal of Investigative Dermatology, 2018.
 
5.     Punicalagin attenuates endothelial dysfunction by activating FoxO1, a pivotal regulating switch of mitochondrial biogenesis.
        Liu X, Cao K, Lv W, Feng Z, Liu J, Gao J, Li H, Zang W, Liu J. 
        Free Radical Biology and Medicine, 2019, 135: 251-260.
 
6.     Surface loops in a single SH2 domain are capable of encoding the spectrum of specificity of the SH2 family.
        Liu H, Huang H, Voss C, Kaneko T, Qin W, Sidhu S, Li S.
        Molecular & Cellular Proteomics, 2019, 18(2): 372-382.
 
7.     Mutation signatures in germline mitochondrial genome provide insights into human mitochondrial evolution and disease
        Gu X, Kang X, Liu J.  
        Human genetics, 2019, 138(6): 613-624.

 

 

2018:

 

1.  ERK-mediated phosphorylation regulates SOX10 sumoylation and targets expression in mutant BRAF melanoma.

Han S, Ren Y, He W, Liu H, Zhi Z, Zhu X, Yang T, Rong Y, Ma B, Purwin TJ, Ouyang Z, Li C, Wang X, Wang X, Yang H, Zheng Y, Aplin AE, Liu J, Shao Y.

 Nat Commun. 2018 Jan 2;9(1):28. doi: 10.1038/s41467-017-02354-x.

 PMID: 29295999


 

 

2. SIRT3/SOD2 maintains osteoblast differentiation and bone formation by regulating mitochondrial stress.

Gao J, Feng Z, Wang X, Zeng M, Liu J, Han S, Xu J, Chen L, Cao K, Long J, Li Z, Shen W, Liu J.

Cell Death Differ. 2018 Feb;25(2):229-240. doi: 10.1038/cdd.2017.144. Epub 2017 Sep 15. 


 

3. APR3 modulates oxidative stress and mitochondrial function in ARPE-19 cells.

Li Y, Zou X, Gao J, Cao K, Feng Z, Liu J.

FASEB J. 2018 May 24:fj201800001RR. doi: 10.1096/fj.201800001RR. [Epub ahead of print]

PMID: 29792731

 

4. A mitochondria-targeting hetero-binuclear Ir(iii)-Pt(ii) complex induces necrosis in cisplatin-resistant tumor cells.

Ouyang C, Chen L, Rees TW, Chen Y, Liu J, Ji L, Long J, Chao H.

Chem Commun (Camb). 2018 Jun 14;54(49):6268-6271. doi: 10.1039/c8cc02795a.

PMID: 29850704

 

5. C10orf99 contributes to the development of psoriasis by promoting the proliferation of keratinocytes.

Chen C, Wu N, Duan Q, Yang H, Wang X, Yang P, Zhang M, Liu J, Liu Z, Shao Y, Zheng Y.

Sci Rep. 2018 Jun 5;8(1):8590. doi: 10.1038/s41598-018-26996-z.

   PMID: 29872130 Free PMC Article

  

6. Human Enteric α-Defensin 5 Promotes Shigella Infection by Enhancing Bacterial Adhesion and Invasion.

Xu D, Liao C, Zhang B, Tolbert WD, He W, Dai Z, Zhang W, Yuan W, Pazgier M, Liu J, Yu J, Sansonetti PJ, Bevins CL, Shao Y, Lu W.

Immunity. 2018 Jun 19;48(6):1233-1244.e7. doi: 10.1016/j.immuni.2018.04.014. Epub 2018 May 29.

PMID: 29858013

 

7. Hydrogen-rich water improves cognitive impairment gender-dependently in APP/PS1 mice without affecting Aβ clearance.

Hou C, Peng Y, Qin C, Fan F, Liu J, Long J.

Free Radic Res. 2018 Apr 23:1-12. doi: 10.1080/10715762.2018.1460749. [Epub ahead of print]

PMID: 29683360

 

8. Mitochondria regulate cardiac contraction through ATP-dependent and independent mechanisms.

Wang K, Xu Y, Sun Q, Long J, Liu J, Ding J.

Free Radic Res. 2018 Apr 3:1-10. doi: 10.1080/10715762.2018.1453137. [Epub ahead of print]

PMID: 29544373

 

 

9. Yes-associated protein promotes the abnormal proliferation of psoriatic keratinocytes via an amphiregulin dependent pathway.

Jia J, Li C, Yang J, Wang X, Li R, Luo S, Li Z, Liu J, Liu Z, Zheng Y.

Sci Rep. 2018 Oct 15;8(1):14513.

 

10. A special issue of SFRR Asia: Cross talk between free radicals and mitochondria in health and disease.

Liu J, Toyokuni S, Surh YJ.

Free Radic Res. 2018 Sep 24:1-51. doi: 10.1080/10715762.2018.1528501.

 

11. Cornulin Is Induced in Psoriasis Lesions and Promotes Keratinocyte Proliferation via Phosphoinositide 3-Kinase/Akt Pathways.

Li C, Xiao L, Jia J, Li F, Wang X, Duan Q, Jing H, Yang P, Chen C, Wang Q, Liu J, Shao Y, Wang N, Zheng Y.

J Invest Dermatol. 2018 Sep 25. pii: S0022-202X(18)32327-3. 

12. Modulation of HIF-2α PAS-B domain contributes to physiological responses.

Feng Z, Zou X, Chen Y, Wang H, Duan Y, Bruick RK.

 Proceedings of the National Academy of Sciences, 2018: 201810897.

 

13.  Oxidative damage of mitochondrial respiratory chain in different organs of a rat model of diet-induced obesity.

Yu H T, Fu X Y, Liang B, Wang S, Liu J, Wang S, Feng Z.

European Journal of Nutrition, 2018, 57(5): 1957-1967.

 

14. Benefits of the soluble and insoluble fractions of bitter gourd in mice fed a high-fat diet.

 Xu J, Cao K, Feng Z, Liu J.

Journal of Functional Foods, 2018, 42: 216-223.

 

15. Synaptotagmin-11 is a critical mediator of parkin-linked neurotoxicity and Parkinson’s disease-like pathology.

Wang C, Kang X, Zhou L, Chai Z, Wu Q, Huang R, Xu H, Hu M, Sun X, Sun S, Li J, Jiao R, Zuo P, Zheng L, Yue Z, Zhou Z.

 Nature Communications, 2018, 9(1): 81.

 

16. 楼静,崔亚娟,刘健康,赵琳. 植物甾醇生理功能的线粒体调控机制《生物化学与生物物理进展》2018(12):1-10

 

17. 张爽曦,龙建纲,刘健康.胰岛素降解酶与阿尔兹海默病的发生[J].中国生物化学与分子生物学报,2018,34(03):249-254.

 

 

2017:

 
1. Early interleukin-6 enhances hepatic ketogenesis in APPSWE/PSEN1dE9 mice via 3-hydroxy-3-methylglutary-CoA synthase 2 signaling activation by p38/nuclear factor κB p65.

Shi L, Zhao D, Hou C, Peng Y, Liu J, Zhang S, Liu J, Long J.

Neurobiol Aging. 2017 Aug;56:115-126. doi: 10.1016/j.neurobiolaging.2017.04.014. Epub 2017 Apr 26.

PMID: 28528772

 

2.Combination of β-glucan and Morus alba L. Leaf Extract Promotes Metabolic Benefits in Mice Fed a High-Fat Diet.

Xu J, Wang X, Cao K, Dong Z, Feng Z, Liu J.

Nutrients. 2017 Oct 12;9(10). pii: E1110. doi: 10.3390/nu9101110.

PMID: 29023387 

 

3. Human β-defensin-3 Induces IL-8 Release and Apoptosis in Airway Smooth Muscle Cells.

Wang W, Qu X, Dang X, Shang D, Yang L, Li Y, Xu D, Martin JG, Hamid Q, Liu J, Chang Y.

Clin Exp Allergy. 2017 Apr 24. doi: 10.1111/cea.12943. [Epub ahead of print]

PMID: 28437599

 

4. Molecular Mechanisms for the Coupling of Endocytosis to Exocytosis in Neurons.

Xie Z, Long J, Liu J, Chai Z, Kang X, Wang C.

Front Mol Neurosci. 2017 Mar 13;10:47. doi: 10.3389/fnmol.2017.00047. eCollection 2017. Review.

PMID: 28348516

 

5. Neurodegenerative Disease Related Proteins Have Negative Effects on SNARE-Mediated Membrane Fusion in Pathological Confirmation.

Hou C, Wang Y, Liu J, Wang C, Long J.

Front Mol Neurosci. 2017 Mar 21;10:66. doi: 10.3389/fnmol.2017.00066. eCollection 2017. No abstract available.

PMID: 28377692

  

6. Oleuropein, unexpected benefits!

Sun W, Frost B, Liu J.

Oncotarget. 2017 Mar 14;8(11):17409. doi: 10.18632/oncotarget.15538. No abstract available.

PMID: 28407695

 

7.Akt activation: A potential strategy to ameliorate insulin resistance.

Zhang Z, Liu H, Liu J.

Diabetes Res Clin Pract. 2017 Oct 27. pii: S0168-8227(17)30315-7. doi: 10.1016/j.diabres.2017.10.004. [Epub ahead of print] Review.

PMID: 29111280

 

8. Endogenously generated amyloid-β increases stiffness in human neuroblastoma cells.

Lu Z, Li H, Hou C, Peng Y, Long J, Liu J.

Eur Biophys J. 2017 Jul;46(5):415-424. doi: 10.1007/s00249-016-1185-3. Epub 2016 Nov 16.

PMID: 27853822

 

9. Oleuropein improves mitochondrial function to attenuate oxidative stress by ctivating the Nrf2 pathway in the hypothalamic paraventricular nucleus of spontaneously hypertensive rats.

Sun W, Wang X, Hou C, Yang L, Li H, Guo J, Huo C, Wang M, Miao Y, Liu J, Kang Y.

Neuropharmacology. 2017 Feb;113(Pt A):556-566. doi: 10.1016/j.neuropharm.2016.11.010. Epub 2016 Nov 12.

PMID: 27847271

 

10. A mix of apple pomace polysaccharide improves mitochondrial function and reduces oxidative stress in the liver of high-fat diet-induced obese mice.

Chen L, Liu L, Li C1, Hu C, Su F, Liu R, Zeng M, Zhao D, Liu J, Guo Y, Long J.

Mol Nutr Food Res. 2017 Mar;61(3). doi: 10.1002/mnfr.201600433. Epub 2017 Jan 31.

 

11. Thinned young apple polysaccharide improves hepatic metabolic disorder in high-fat diet-induced obese mice by activating mitochondrial respiratory functions.

Chen, L, Yang, X, Liu, R, Liu L, Zhao D, Liu J, Guo Y, Long J.

Journal of Functional Foods, 2017, 33: 396-407.

 

12. 樊璠 , 龙建纲 , 刘健康 .阿尔茨海默病早期诊断的体液生物标志物《生命科学研究》 , 2017 (4) :370-376

 

 

 

2016:

 

1. O-GlcNAcase deficiency suppresses skeletal myogenesis and insulin sensitivity in mice through the modulation of mitochondrial homeostasis.

Wang X, Feng Z, Wang X, Yang L, Han S, Cao K, Xu J, Zhao L, Zhang Y, Liu J.

Diabetologia. 2016 Jun;59(6):1287-96. doi: 10.1007/s00125-016-3919-2. Epub 2016 Mar 18.

PMID:26993634

 


 


2.Three-dimensional structural dynamics and fluctuations of DNA-nanogold conjugates by individual-particle electron tomography.

Zhang L, Lei D, Smith JM, Zhang M, Tong H, Zhang X, Lu Z, Liu J, Alivisatos AP, Ren G.


Nat Commun. 2016 Mar 30;7:11083. doi: 10.1038/ncomms11083.


PMID:27025159
Similar articles
 


 

3. Molecular Architecture of Contactin-associated Protein-like 2 (CNTNAP2) and Its Interaction with Contactin 2 (CNTN2).


Lu Z, Reddy MV, Liu J, Kalichava A, Liu J, Zhang L, Chen F, Wang Y, Holthauzen LM, White MA, Seshadrinathan S, Zhong X, Ren G, Rudenko G.


J Biol Chem. 2016 Nov 11;291(46):24133-24147.


PMID: 27621318

 

4.Cdh1 regulates craniofacial development via APC-dependent ubiquitination and activation of Goosecoid.


Shao R, Liu J, Yan G, Zhang J, Han Y, Guo J, Xu Z, Yuan Z, Liu J, Malumbres M, Wan L, Wei W, Zou W.


Cell Res. 2016 Apr 29. doi: 10.1038/cr.2016.51.


PMID:27126000

 


 

5. Cdh1 inhibits WWP2-mediated ubiquitination of PTEN to suppress tumorigenesis in an APC-independent manner.


Liu J, Wan L, Liu J, Yuan Z, Zhang J, Guo J, Malumbres M, Liu J, Zou W, Wei W.


Cell Discov. 2016 Feb 2;2:15044. doi: 10.1038/celldisc.2015.44.


PMID: 27462441 Free PMC Article
Select item 27422330

 

6. Real-time tracking mitochondrial dynamic remodeling with two-photon phosphorescent iridium (III) complexes.


Huang H, Yang L, Zhang P, Qiu K, Huang J, Chen Y, Diao J, Liu J, Ji L, Long J, Chao H.


Biomaterials. 2016 Mar;83:321-31. doi: 10.1016/j.biomaterials.2016.01.014. Epub 2016 Jan 6.


PMID:26796044

 

 

7. Programming Saposin-Mediated Compensatory Metabolic Sinks for Enhanced Ubiquinone Production.


Xu W, Yuan J, Yang S, Ching CB, Liu J.


ACS Synth Biol. 2016 Jul 14. [Epub ahead of print]


PMID: 27389347

 

8. Coral calcium hydride prevents hepatic steatosis in high fat diet-induced obese rats: A potent mitochondrial nutrient and phase II enzyme inducer.


Hou C, Wang Y, Zhu E, Yan C, Zhao L, Wang X, Qiu Y, Shen H, Sun X, Feng Z, Liu J, Long J.


Biochem Pharmacol. 2016 Mar 1;103:85-97. doi: 10.1016/j.bcp.2015.12.020. Epub 2016 Jan 13.


PMID:26774456

 

 

9. Mitochondrial dysfunction precedes depression of AMPK/AKT signaling in insulin resistance induced by high glucose in primary cortical neurons.

Peng Y, Liu J, Shi L, Tang Y, Gao D, Long J, Liu J.


J Neurochem. 2016 Jun;137(5):701-13. doi: 10.1111/jnc.13563. Epub 2016 Apr 18.


PMID:26926143

 


 

10. Early inflammation-associated factors blunt sterol regulatory element-binding proteins-1-mediated lipogenesis in high-fat diet-fed APPSWE /PSEN1dE9 mouse model of Alzheimer's disease.

Tang Y, Peng Y, Liu J, Shi L, Wang Y, Long J, Liu J.

J Neurochem. 2015 Nov 18. doi: 10.1111/jnc.13437. [Epub ahead of print]

PMID:  26578392

 

11. Hydroxytyrosol mildly improve cognitive function independent of APP processing in APP/PS1 mice.


Peng Y, Hou C, Yang Z, Li C, Jia L, Liu J, Tang Y, Shi L, Li Y, Long J, Liu J.


Mol Nutr Food Res. 2016 Nov;60(11):2331-2342. doi: 10.1002/mnfr.201600332.


PMID: 27287957

 

12. Punicalagin attenuates palmitate-induced lipotoxicity in HepG2 cells by activating the Keap1-Nrf2 antioxidant defense system.

Yan C, Sun W, Wang X, Long J, Liu X, Feng Z, Liu J.


Mol Nutr Food Res. 2016 May;60(5):1139-49. doi: 10.1002/mnfr.201500490. Epub 2016 Apr 14.


PMID:26989875

 


 


13. Apple pomace polysaccharides improves mitochondrial function and reduces oxidative stress in the liver of high-fat diet-induced obese mice.


Chen L, Liu L, Li C, Hu C, Su F, Liu R, Zeng M, Zhao D, Liu J, Guo Y, Long J.


Mol Nutr Food Res. 2016 Sep 12. doi: 10.1002/mnfr.201600433. [Epub ahead of print]


PMID: 27615442
Select item 27462441

 

14. Pomegranate extract and exercise provide additive benefits on improvement of immune function by inhibiting inflammation and oxidative stress in high-fat-  diet-induced obesity in rats.

Zhao F, Pang W, Zhang Z, Zhao J, Wang X, Liu Y, Wang X, Feng Z, Zhang Y, Sun W, Liu J.


J Nutr Biochem. 2016 Jun;32:20-8. doi: 10.1016/j.jnutbio.2016.02.003. Epub 2016 Feb 28.


PMID:27142733

 


 

15. Pomegranate extract decreases oxidative stress and alleviates mitochondrial impairment by activating AMPK-Nrf2 in hypothalamic paraventricular nucleus of spontaneously hypertensive rats.


Sun W, Yan C, Frost B, Wang X, Hou C, Zeng M, Gao H, Kang Y, Liu J.


Sci Rep. 2016 Oct 7;6:34246. doi: 10.1038/srep34246.


PMID:27713551

 

16. The regulatory roles of O-GlcNAcylation in mitochondrial homeostasis and metabolic syndrome.

Zhao L, Feng Z, Yang X, Liu J.


Free Radic Res. 2016 Oct;50(10):1080-1088.


PMID: 27646831


 

17. Neuroprotective effects of methane-rich saline on experimental acute carbon monoxide toxicity. 


Shen M, Fan D, Zang Y, Chen Y, Zhu K, Cai Z, Liu Y, Sun X, Liu J, Gong J.


J Neurol Sci. 2016 Oct 15;369:361-7. doi: 10.1016/j.jns.2016.08.055.


PMID:27653924

 

18. SNARE-mediated membrane fusion in autophagy.


Wang Y, Li L, Hou C, Lai Y, Long J, Liu J, Zhong Q, Diao J.


Semin Cell Dev Biol. 2016 Jul 12. pii: S1084-9521(16)30204-X. doi: 10.1016/j.semcdb.2016.07.009. [Epub ahead of print] Review.


PMID: 27422330




 

19. Measuring Redox Status of Melanoma Cells.


Liu-Smith F, Krasieva TB, Liu J, Liu J, Meyskens FL Jr.
Methods Mol Biol. 2016 Apr 10. [Epub ahead of print]


PMID:27062599

 


 

20. Intrinsic and membrane-facilitated α-synuclein oligomerization revealed by label-free detection through solid-state nanopores.


Hu R, Diao J, Li J, Tang Z, Li X, Leitz J, Long J, Liu J, Yu D, Zhao Q.
Sci Rep. 2016 Feb 11;6:20776. doi: 10.1038/srep20776.


PMID:26865505
Free PMC Article

 


 

21. Hydrogen Inhalation is Superior to Mild Hypothermia in Improving Cardiac Function and Neurological Outcome in an Asphyxial Cardiac Arrest Model of Rats.


Wang P, Jia L, Chen B, Zhang L, Liu J, Long J, Li Y.


Shock. 2016 Feb 3.

[Epub ahead of print]
PMID:26849632

 


 


22.Oleuropein improves mitochondrial function to attenuate oxidative stress by activating the Nrf2 pathway in the hypothalamic paraventricular nucleus of spontaneously hypertensive rats.

Sun W, Wang X, Hou C, Yang L, Li H, Guo J, Huo C, Wang M, Miao Y, Liu J, Kang Y.

Neuropharmacology. 2016 Nov 12;113(Pt A):556-566. doi: 10.1016/j.neuropharm.2016.11.010. [Epub ahead of print]

PMID: 27847271

 
 
 

 

2015:


1.Punicalagin, an active component in pomegranate, ameliorates cardiac mitochondrial impairment in obese rats via AMPK activation.
Cao K, Xu J, Pu W, Dong Z, Sun L, Zang W, Gao F, Zhang Y, Feng Z, Liu J.
Sci Rep. 2015 Sep 15;5:14014. doi: 10.1038/srep14014.
PMID:  26369619 
 

 

2.OM2, a Novel Oligomannuronate-Chromium(III) Complex, Promotes Mitochondrial Biogenesis and Lipid Metabolism in 3T3-L1 Adipocytes via the AMPK-PGC1α Pathway.
Hao J, Hao C, Zhang L, Liu X, Zhou X, Dun Y, Li H, Li G, Zhao X, An Y, Liu J, Yu G.
PLoS One. 2015 Jul 15;10(7):e0131930. doi: 10.1371/journal.pone.0131930. eCollection 2015.
PMID:  26176781 
  

3.SIRT3 Enhances Glycolysis and Proliferation in SIRT3-Expressing Gastric Cancer Cells.
Cui Y, Qin L, Wu J, Qu X, Hou C, Sun W, Li S, Vaughan AT, Li JJ, Liu J.
PLoS One. 2015 Jun 29;10(6):e0129834. doi: 10.1371/journal.pone.0129834. eCollection 2015.
PMID:  26121691 
 

4.Lipoamide Acts as an Indirect Antioxidant by Simultaneously Stimulating Mitochondrial Biogenesis and Phase II Antioxidant Enzyme Systems in ARPE-19 Cells.
Zhao L, Liu Z, Jia H, Feng Z, Liu J, Li X.
PLoS One. 2015 Jun 1;10(6):e0128502. doi: 10.1371/journal.pone.0128502. eCollection 2015.
PMID:  26030919 
  

5.Phosphatase and tensin homolog-induced putative kinase 1 and Parkin in diabetic heart: Role of mitophagy.
Tang Y, Liu J, Long J.
J Diabetes Investig. 2015 May;6(3):250-5. doi: 10.1111/jdi.12302. Epub 2014 Dec 16. Review.
PMID:  25969707
  

6.Lipid molecules influence early stages of yeast SNARE-mediated membrane fusion.
Lai Y, Zhao L, Bu B, Lou X, Li D, Ji B, Liu J, Diao J, Shin YK.
Phys Biol. 2015 Apr 21;12(2):025003. doi: 10.1088/1478-3975/12/2/025003.
PMID:  25898400
  

7.Hydroxytyrosol improves mitochondrial function and reduces oxidative stress in the brain of db/db mice: role of AMP-activated protein kinase activation.
Zheng A, Li H, Xu J, Cao K, Li H, Pu W, Yang Z, Peng Y, Long J, Liu J, Feng Z.
Br J Nutr. 2015 Jun 14;113(11):1667-76. doi: 10.1017/S0007114515000884. Epub 2015 Apr 17.
PMID:  25885653
  

8.Maternal hydroxytyrosol administration improves neurogenesis and cognitive function in prenatally stressed offspring.
Zheng A, Li H, Cao K, Xu J, Zou X, Li Y, Chen C, Liu J, Feng Z.
J Nutr Biochem. 2015 Feb;26(2):190-9. doi: 10.1016/j.jnutbio.2014.10.006. Epub 2014 Nov 12.
PMID:  25442671
 

 

2014:
 
1. Genomic signatures of near-extinction and rebirth of the crested ibis and other endangered bird species.
Li S, Li B, Cheng C, Xiong Z, Liu Q, Lai J, Carey HV, Zhang Q, Zheng H, Wei S, Zhang H, Chang L, Liu S, Zhang S, Yu B, Zeng X, Hou Y, Nie W, Guo Y, Chen T, Han J, Wang J, Wang J, Chen C, Liu J, Stambrook PJ, Xu M, Zhang G, Gilbert MT, Yang H, Jarvis ED, Yu J, Yan J.
Genome Biol. 2014;15(12):557.
PMID: 25496777 Free PMC Article
 
2. Activation of Erk and p53 regulates copper oxide nanoparticle-induced cytotoxicity in keratinocytes and fibroblasts.
Luo C, Li Y, Yang L, Zheng Y, Long J, Jia J, Xiao S, Liu J.
Int J Nanomedicine. 2014 Oct 10;9:4763-72. doi: 10.2147/IJN.S67688. eCollection 2014.
PMID: 25336953   Free PMC Article
 
3. High-Fat-Diet-Induced Weight Gain Ameliorates Bone Loss without Exacerbating AβPP Processing and Cognition in Female APP/PS1 Mice.
Peng Y, Liu J, Tang Y, Liu J, Han T, Han S, Li H, Hou C, Liu J, Long J.
Front Cell Neurosci. 2014 Aug 8;8:225. doi: 10.3389/fncel.2014.00225. eCollection 2014.
PMID: 25152713   Free PMC Article

4. AMPK activation prevents prenatal stress-induced cognitive impairment: modulation of mitochondrial content and oxidative stress.
Cao K, Zheng A, Xu J, Li H, Liu J, Peng Y, Long J, Zou X, Li Y, Chen C, Liu J, Feng Z.
Free Radic Biol Med. 2014 Oct;75:156-66. doi: 10.1016/j.freeradbiomed.2014.07.029. Epub 2014 Aug 1.
PMID: 25091899
 
5. Coexpression within Integrated Mitochondrial Pathways Reveals Different Networks in Normal and Chemically Treated Transcriptomes.
Chen C, Hyun TK, Han X, Feng Z, Li Y, Liu X, Liu J.
Int J Genomics. 2014;2014:452891. doi: 10.1155/2014/452891. Epub 2014 Jun 24.
PMID: 25089262  Free PMC Article
 

6. Acetylated FoxO1 mediates high-glucose induced autophagy in H9c2 cardiomyoblasts: regulation by a polyphenol -(-)-epigallocatechin-3-gallate.
Liu J, Tang Y, Feng Z, Hou C, Wang H, Yan J, Liu J, Shen W, Zang W, Liu J, Long J.
Metabolism. 2014 Oct;63(10):1314-23. doi: 10.1016/j.metabol.2014.06.012. Epub 2014 Jun 19.
PMID:25062567
 
7. Aging leads to elevation of O-GlcNAcylation and disruption of mitochondrial homeostasis in retina.
Zhao L, Feng Z, Zou X, Cao K, Xu J, Liu J.
Oxid Med Cell Longev. 2014;2014:425705. doi: 10.1155/2014/425705. Epub 2014 May 29.
PMID:24987494  Free PMC Article
  
8. LL-37 attenuates inflammatory impairment via mTOR signaling-dependent mitochondrial protection.
Sun W, Zheng Y, Lu Z, Wang H, Feng Z, Wang J, Xiao S, Liu F, Liu J.
Int J Biochem Cell Biol. 2014 Sep;54:26-35. doi: 10.1016/j.biocel.2014.06.015. Epub 2014 Jun 28.
PMID: 24984264
 
9. Hydroxytyrosol induces apoptosis in human colon cancer cells through ROS generation.
Sun L, Luo C, Liu J.
Food Funct. 2014 Aug;5(8):1909-14. doi: 10.1039/c4fo00187g.
PMID: 24953710

10.Improving coenzyme Q8 production in Escherichia coli employing multiple strategies.
Xu W, Yang S, Zhao J, Su T, Zhao L, Liu J.
J Ind Microbiol Biotechnol. 2014 Aug;41(8):1297-303. doi: 10.1007/s10295-014-1458-8. Epub 2014 Jun 8.
PMID: 24907944
 
11. Mitochondrial JNK activation triggers autophagy and apoptosis and aggravates myocardial injury following ischemia/reperfusion.
Xu J, Qin X, Cai X, Yang L, Xing Y, Li J, Zhang L, Tang Y, Liu J, Zhang X, Gao F.
Biochim Biophys Acta. 2015 Feb;1852(2):262-70. doi: 10.1016/j.bbadis.2014.05.012. Epub 2014 May 21.
PMID:24859228
 
12. Superparamagnetic iron oxide nanoparticles exacerbate the risks of reactive oxygen species-mediated external stresses.
Luo C, Li Y, Yang L, Wang X, Long J, Liu J.
Arch Toxicol. 2015 Mar;89(3):357-69. doi: 10.1007/s00204-014-1267-x. Epub 2014 May 22.
PMID: 24847785
 
13. 4-methylene-2-octyl-5-oxotetrahydrofuran-3-carboxylic acid (C75), an inhibitor of fatty-acid synthase, suppresses the mitochondrial fatty acid synthesis pathway and impairs mitochondrial function.
Chen C, Han X, Zou X, Li Y, Yang L, Cao K, Xu J, Long J, Liu J, Feng Z.
J Biol Chem. 2014 Jun 13;289(24):17184-94. doi: 10.1074/jbc.M114.550806. Epub 2014 May 1.
PMID:24784139

14. Mitochondrial free radical theory of aging: who moved my premise?
Liu Y, Long J, Liu J.
Geriatr Gerontol Int. 2014 Oct;14(4):740-9. doi: 10.1111/ggi.12296. Epub 2014 Apr 18.
PMID: 24750368
 
15. Overexpression of S100A7 protects LPS-induced mitochondrial dysfunction and stimulates IL-6 and IL-8 in HaCaT cells.
Sun W, Zheng Y, Lu Z, Cui Y, Tian Q, Xiao S, Liu F, Liu J.
PLoS One. 2014 Mar 26;9(3):e92927. doi: 10.1371/journal.pone.0092927. eCollection 2014.
PMID: 24671027   

16. Gold nanoparticle wires for sensing DNA and DNA/protein interactions.
Shao L, Diao JJ, Tang Z, Liu S, Shen SC, Liu J, Rui X, Yu D, Zhao Q.
Nanoscale. 2014 Apr 21;6(8):4089-95. doi: 10.1039/c3nr06560j. Epub 2014 Mar 4.
PMID: 24589712

 
17. Bitter gourd inhibits the development of obesity-associated fatty liver in C57BL/6 mice fed a high-fat diet.
Xu J, Cao K, Li Y, Zou X, Chen C, Szeto IM, Dong Z, Zhao Y, Shi Y, Wang J, Liu J, Feng Z.
J Nutr. 2014 Apr;144(4):475-83. doi: 10.3945/jn.113.187450. Epub 2014 Feb 12.
PMID: 24523491   


18. Evidence for association of mitochondrial metabolism alteration with lipid accumulation in aging rats.
Zhao L, Zou X, Feng Z, Luo C, Liu J, Li H, Chang L, Wang H, Li Y, Long J, Gao F, Liu J.
Exp Gerontol. 2014 Aug;56:3-12. doi: 10.1016/j.exger.2014.02.001. Epub 2014 Feb 8.
PMID: 24518876
 
19. D-galactose induces a mitochondrial complex I deficiency in mouse skeletal muscle: potential benefits of nutrient combination in ameliorating muscle impairment.
Chang L, Liu X, Liu J, Li H, Yang Y, Liu J, Guo Z, Xiao K, Zhang C, Liu J, Zhao-Wilson X, Long J.
J Med Food. 2014 Mar;17(3):357-64. doi: 10.1089/jmf.2013.2830. Epub 2014 Jan 29.
PMID: 24476218  
  
20. Reloading functionally ameliorates disuse-induced muscle atrophy by reversing mitochondrial dysfunction, and similar benefits are gained by administering a combination of mitochondrial nutrients.
Liu J, Peng Y, Feng Z, Shi W, Qu L, Li Y, Liu J, Long J.
Free Radic Biol Med. 2014 Apr;69:116-28. doi: 10.1016/j.freeradbiomed.2014.01.003. Epub 2014 Jan 10.
PMID: 24418157

21. Mitochondrial dysfunction in obesity-associated nonalcoholic fatty liver disease: the protective effects of pomegranate with its active component punicalagin.
Zou X, Yan C, Shi Y, Cao K, Xu J, Wang X, Chen C, Luo C, Li Y, Gao J, Pang W, Zhao J, Zhao F, Li H, Zheng A, Sun W, Long J, Szeto IM, Zhao Y, Dong Z, Zhang P, Wang J, Lu W, Zhang Y, Liu J, Feng Z.
Antioxid Redox Signal. 2014 Oct 10;21(11):1557-70. doi: 10.1089/ars.2013.5538. Epub 2014 Feb 18.
PMID:24393106   


 
22. SCF(β-TRCP)-mediated degradation of NEDD4 inhibits tumorigenesis through modulating the PTEN/Akt signaling pathway.
Liu J, Wan L, Liu P, Inuzuka H, Liu J, Wang Z, Wei W.
Oncotarget. 2014 Feb 28;5(4):1026-37.
PMID: 24657926 


 
23. Compromised mitochondrial remodeling in compensatory hypertrophied myocardium of spontaneously hypertensive rat.
Tang Y, Mi C, Liu J, Gao F, Long J.
Cardiovasc Pathol. 2014 Mar-Apr;23(2):101-6. doi: 10.1016/j.carpath.2013.11.002. Epub 2013 Nov 14.
PMID: 24388463
 
24.Aerobic interval training attenuates mitochondrial dysfunction in rats post-myocardial infarction: roles of mitochondrial network dynamics
Jiang HK, Wang YH, Sun L, He X, Zhao M, Feng ZH, Yu XJ, Zang WJ.
Int J Mol Sci. 2014 Mar 26;15(4):5304-22. doi: 10.3390/ijms15045304
PMID: 24675698  

 
25.Aerobic interval training protects against myocardial infarction-induced oxidative injury by enhancing antioxidasesystem and mitochondrial biosynthesis.
Jiang HK1, Miao Y, Wang YH, Zhao M, Feng ZH, Yu XJ, Liu JK, Zang WJ.
Clin Exp Pharmacol Physiol. 2014 Mar;41(3):192-201. doi: 10.1111/1440-1681.12211
PMID: 24471974

 
26. Zeaxanthin induces Nrf2-mediated phase II enzymes in protection of cell death.
Zou X, Gao J, Zheng Y, Wang X, Chen C, Cao K, Xu J, Li Y, Lu W, Liu J, Feng Z.
Cell Death Dis. 2014 May 8;5:e1218. doi: 10.1038/cddis.2014.190.


27. Mitochondrial dysfunction-associated OPA1 cleavage contributes to muscle degeneration: preventative effect of hydroxytyrosol acetate.
Wang X, Li H, Zheng A, Yang L, Liu J, Chen C, Tang Y, Zou X, Li Y, Long J, Liu J, Zhang Y, Feng Z.
Cell Death Dis. 2014 Nov 13;5:e1521. doi: 10.1038/cddis.2014.473.
 
 

 

2013:
 
1. A novel signal transduction pathway from TGF-1 to SKP2 via Akt1 and c-Myc and its correlation with progression in human melanoma.
Qu X, Shen L, Zheng Y, Cui Y, Feng Z, Liu F, and Liu J
J Invest Dermatol (IF 6.3), 2013 (in press).

 
2. Hydroxytyrosol induces apoptosis and mitochondrial dysfunction of human prostate cancer cells by causing superoxide production and autophagic defect.
Luo C, Wang H, Li Y, Cui Y, Feng Z, Li H, Li Y, Wang Y, Wurtz K, Weber P, Long J and Liu J
 Curr Cancer Drug Target (IF 4.3), 2013 (in press).

 
3. Oxidative stress mediates chemerin-induced autophagy in endothelial cells.
Shen W, Tian C, Chen H, Yang Y, Zhu D, Gao P, Liu J.
Free Radic Biol Med. 2013Feb;55:73-82.doi:10.1016/j.freeradbiomed.2012.11.011. Epub 2012 Nov 27.


 4. Mitochondrial accumulation under oxidative stress is due to defects in autophagy.  
 Luo C, Li Y, Wang H, Feng Z, Li Y, Long J, Liu J.
 J Cell Biochem, 2012 Aug 17. doi: 10.1002/jcb.24356. [Epub ahead of print]; 2013 Jan;114(1):212-9.
 
5. A complex dietary supplement augments spatial learning, brain mass and mitochondrial electron transport chain activity in aging mice.
Aksenov V, Long J, Liu J*, Szechtman H, Khanna P, Matravadia S, Rollo CD*
AGE,2013 Feb;35(1):23-33. doi: 10.1007/s11357-011-9325-2. Epub 2011 Nov 27. 
 
 

6. Curcumin analogue 1, 5-Bis (2-trifluoromethylphenyl)-1, 4-pentadien-3-one exhibit enhanced ability on Nrf2 activation and protection against acrolein-induced ARPE-19 cell toxicity.Toxicol Appl Pharmacol.
Li Y, Zou X, Cao K, Xu J, Yue T, Dai F, Zhou B, Lu W, Feng Z, Liu J
2013 Aug 13. doi:pii: S0041-008X(13)00339-6. 10.1016/j.taap.2013.07.029. [Epub ahead of print] 


 7.  A cigarette component acrolein induces accelerated senescence in human diploid fibroblast IMR-90 cells.
Luo C, Li Y, Yang L, Feng Z, Li Y, Long J, Liu J
Biogerontology. 2013 Sep 12. [Epub ahead of print] 


 8.  Protection of H9c2 rat cardiomyoblasts against oxidative insults by total paeony glucosides from Radix Paeoniae Rubrae.
Luo C, Wang H, Chen X, Cui Y, Li H, Long J, Mo X, Liu J
Phytomedicine. 2013 Sep 12. doi:pii: S0944-7113(13)00284-5. 10.1016/j.phymed.2013.08.002. [Epub ahead of print]
 
 9.  Studying protein-reconstituted proteoliposome fusion with content indicators in vitro. 
 Diao J, Zhao M, Zhang Y, Kyoung M, Brunger AT
Bioessays. 2013 Jul;35(7):658-65. doi: 10.1002/bies.201300010. Epub 2013 Apr 29.


 
10.  Fusion pore formation and expansion induced by Ca2+ and synaptotagmin 1.
Lai Y, Diao J, Liu Y, Ishitsuka Y, Su Z, Schulten K, Ha T, Shin YK
 Proc Natl Acad Sci USA. 2013 Jan 22;110(4):1333-8. doi: 10.1073/pnas.1218818110. Epub 2013 Jan 8. 

 
11. O-GlcNAc transferase/host cell factor C1 complex regulates gluconeogenesis by modulating PGC-1α stability. 
Ruan HB, Han X, Li MD, Singh JP, Qian K, Azarhoush S, Zhao L, Bennett AM, Samuel VT, Wu J, Yates JR 3rd, Yang X
Cell Metab. 2012 Aug 8;16(2):226-37. doi: 10.1016/j.cmet.2012.07.006.

 
12.  A monocarbonyl analogue of curcumin, 1,5-bis(3-hydroxyphenyl)-1,4-pentadiene-3-one (Ca37), exhibits potent growth suppressive activity and enhances the inhibitory effect of curcumin on human prostate cancer cells.
Cheng Luo, Yan Li, Bo Zhou, Liang Yang, Hua Li, Zhihui Feng, Yuan Li, Jiangang Long,  Jiankang Liu
Apoptosis (IF 3.9). (in press)

 
13.  Anticancer Effect of a Curcumin Derivative B63: ROS Production and Mitochondrial Dysfunction Curr Cancer Drug Target.
Adi Zheng, 1Hao Li, 1Xun Wang, 1Zhihui Feng, 1Jie Xu, 1Ke Cao, 2Bo Zhou, 1*Jing Wu, and 1*Jiankang Liu
(IF 4.0), (in press).

 
14.  Hydroxytyrosol prevents diet-induced metabolic syndrome and attenuates mitochondrial abnormalities in obese mice.
 Cao K, Xu J, Zou X, Li Y, Chen C, Zheng A, Li H, Li H, Szeto IM, Shi Y, Long J, Liu J*, Feng Z*.
 Free Radic Biol Med.  2013 Dec 6; 67C:396-407. doi: 10.1016/j.freeradbiomed.2013.11.029. [Epub ahead of print]

 
15. Adhesive protein-free synthetic hydrogels for retinal pigment epithelium cell culture with low ROS level. 
Chen YM, Liu ZQ, Feng ZH, Xu F,Liu J.
J Biomed Mater Res A. 2013 Aug 3. doi: 10.1002/jbm.a.34904. [Epub ahead of print]

 
16. Compromised mitochondrial remodeling in compensatory hypertrophied myocardium of spontaneously hypertensive rat. 
Tang Y, Mi C, Liu J, Gao F, Long J.
Cardiovasc Pathol. 2013 Nov 14. [Epub ahead of print]


17. Curcumin analogue 1, 5-Bis (2-trifluoromethylphenyl)-1, 4-pentadien-3-one exhibit enhanced ability on Nrf2 activation and protection against acrolein-induced ARPE-19 cell toxicity.
 Li Y, Zou X, Cao K, Xu J, Yue T, Dai F, Zhou B, Lu W, Feng Z, Liu J
Toxicol Appl Pharmacol (IF 3.975) 2013 Aug 13. [Epub ahead of print]

  
18. Cardioprotection by acetylcholine: a novel mechanism via mitochondrial biogenesis and function involving the PGC-1α pathway. 
 Sun L, Zhao M, Yu XJ, Wang H, He X, Liu JK, Zang WJ
 J Cell Physiol. 2013 Jun;228(6):1238-48. doi: 10.1002/jcp.24277. 


 
 
2012:
 
1. Maternal docosahexaenoic acid feeding protects against impairment of learning and memory and oxidative stress in prenatally stressed rats: Possible role of neuronal mitochondria metabolism.
Feng Z, Zou X, Jia H, Li X, Zhu Z, Liu X, Bucheli P, Ballevre O, Hou Y, Zhang W, Wang J, Chen Y, Liu J*.
Antioxid Redox Signal (IF 8.2) 16(3):275-89; 2012
 
2. Enhanced autophagy plays a cardinal role in mitochondrial dysfunction in type 2 diabetic goto-kakizaki (gk) rats: Ameliorating effects of (-)-epigallocatechin-3-gallate.
Yan J, Feng Z, Liu J, Shen W, Wang Y, Wertz K, Weber P, Long J*, Liu J.
J Nutr Biochem. 2012;23:716-724

 
3. Stimulation of GSH synthesis to prevent oxidative stress-induced apoptosis by hydroxytyrosol in human retinal pigment epithelial cells: Activation of nrf2 and jnk-p62/sqstm1 pathways. 
Zou X, Feng Z, Li Y, Wang Y, Wertz K, Weber P, Fu Y, Liu J*.
J Nutr Biochem. 2012;23:994-1006 
 
4. Metabolic module mining based on independent component analysis in arabidopsis thaliana.
Han X, Chen C, Hyun TK, Kumar R, Kim JY.
 Mol Cells. 2012;34:295-304

 
5. New evidence of mitochondria dysfunction in the female alzheimer's disease brain: Deficiency of estrogen receptor-beta.
Long J, He P, Shen Y, Li R.
J Alzheimers Dis. 2012;30:545-558 

 
6. Cardioprotective effect of total paeony glycosides against isoprenaline-induced myocardial ischemia in rats.
Long J, Gao M, Kong Y, Shen X, Du X, Son YO, Shi X, Liu J, Mo X.
Phytomedicine. 2012;19:672-676

 
7. A complex dietary supplement modulates nitrative stress in normal mice and in a new mouse model of nitrative stress and cognitive aging. 
Long J, Aksenov V, Rollo CD, Liu J.
Mech Ageing Dev. 2012;133:523-529 

 
8. Depressed mitochondrial biogenesis and dynamic remodeling in mouse tibialis anterior and gastrocnemius induced by 4-week hindlimb unloading.
Liu J, Peng Y, Cui Z, Wu Z, Qian A, Shang P, Qu L, Li Y,Long J*, Liu J*.
IUBMB Life. 2012

 
9. Mitochondrial energy metabolism plays a critical role in the cardioprotection afforded by intermittent hypobaric hypoxia.
Wang ZH, Cai XL, Wu L, Yu Z, Liu JL, Zhou ZN, Liu J*, Yang HT*.
Exp Physiol. 2012;97:1105-1118
 
10. Reactive Oxygen Species Mediate Cr(VI)-induced S Phase Arrest Through p53 in Human Colon Cancer Cells.
Sun L, Wang X, Yao H, Li W, Son YO, Luo J, Liu J, Zhang Z
J Environ Pathol Toxicol Oncol. 2012;31(2):95-107.
 

11.  基于原子力显微镜的细胞弹性测量及分析方法.
鲁卓阳,龙建纲,李涤尘,刘健康. 
电子显微学报 31(4), 54-60. 2012,中文核心期刊
 
12.  脑内线粒体雌激素受体β在女性阿尔茨海默病发生过程中的作用[J].
刘健康, 彭韵桦, 龙建纲.
生物化学与生物物理进展39(8): 785~790. 2012,中文核心期刊
 
13.  羟基酪醇作为线粒体营养素的调控机制
罗成,刘健康
生命科学. 2012,中文核心期刊(已录用)
 
14.  氢医学研究及可能的线粒体机制.
侯晨,龙建纲,刘健康
医学综述. 2012,中国科技核心期刊(已录用)
 
15.  阿尔茨海默病(Alzheimerˊs Disease)与动力相关蛋白1(dynamin-related protein 1,Drp1).
李华,龙建纲,刘健康. (2012). 
生物学杂志.中国科技核心期刊(已录用)
 
16. O-GlcNAc transferase is involved in glucocorticoid receptor-mediated transrepression.
Li, Min-Dian, Hai-Bin Ruan, Jay P. Singh, Lin Zhao, Tingting Zhao, Sascha Azarhoush, Jing Wu, Ronald M. Evans, and Xiaoyong Yang.
Journal of Biological Chemistry 287, no. 16 (2012): 12904-12912.
 
17. Reactive Oxygen Species Mediate Cr(VI)-induced S Phase Arrest Through p53 in Human Colon Cancer Cells.
Sun L, Wang X, Yao H, Li W, Son YO, Luo J, Liu J, Zhang Z
J Environ Pathol Toxicol Oncol. 2012;31(2):95-107.
 
 

 2011:
 
1. Mitochondrial dynamic remodeling in strenuous exercise-induced muscle and rnitochondrial dysfunction: Regulatory effects of hydroxytyrosol. 
Feng Z, Bai L, Yan J, Li Y, Shen W, Wang Y, Wertz K, Weber P, Zhang Y, Chen Y, Liu J*.
Free Radical Bio Me. 2011;50:1437-1446 

 
2. Mitochondrial dysfunction in the liver of type 2 diabetic goto-kakizaki rats: Improvement by a combination of nutrients. 
Hao J, Shen W, Sun L, Long J, Sharman E, Shi X, Liu J*.
Br J Nutr. 2011;106:648-655 

 
3. Induction of oxidative stress and DNA damage in cervix in acute treatment with benzo[a]pyrene.
Gao M, Li Y, Long J, Shah W, Fu L, Lai B, Wang Y.
Mutat Res. 2011;719:52-59

 
4. A common carcinogen benzo[a]pyrene causes p53 overexpression in mouse cervix via DNA damage. 
Gao M, Li Y, Sun Y, Long J, Kong Y, Yang S, Wang Y.
Mutat Res. 2011;724:69-75 

 
5. Benzo[a]pyrene exposure increases toxic biomarkers and morphological disorders in mouse cervix.
Gao M, Li Y, Sun Y, Shah W, Yang S, Wang Y, Long J.
Basic Clin Pharmacol Toxicol. 2011;109:398-406
  
6. The protective effect of peony extract on acute myocardial infarction in rats.
Mo X, Zhao N, Du X, Bai L, Liu J*.
Phytomedicine. 2011;18:451-457 

7. Luteolin protects against reactive oxygen species-mediated cell death induced by zinc toxicity via the pi3k-akt-nf-kappab-erk-dependent pathway. 
Zhou F, Qu L, Lv K, Chen H, Liu J, Liu X, Li Y, Sun X.
J Neurosci Res. 2011;89:1859-1868  

 
8. Activation of akt/gsk3beta and akt/bcl-2 signaling pathways in nickel-transformed beas-2b cells. 
Pan JJ, Chang QS, Wang X, Son YO, Liu J, Zhang Z, Bi YY, Shi X.
Int J Oncol. 2011;39:1285-1294 

 
9. Adenine sulfate improves cardiac function and the cardiac cholinergic system after myocardial infarction in rats.
Sun L, Lu J, Yu XJ, Li DL, Xu XL, Wang B, Ren KY, Liu J, Zang WJ.
J Pharmacol Sci. 2011;115:205-213 

 
10. Well-functioning cell mitochondria promote good health.
 Chowanadisai W, Shenoy SF, Sharman E, Keen CL, Liu J, Rucker RB.
Calif Agr. 2011;65:136-140  

 
11.Biofactors in food promote health by enhancing mitochondrial function.
Shenoy SF, Chowanadisai W, Sharman E, Keen CL, Liu J, Rucker RB.
Calif Agr. 2011;65:141-147 

 
12. Protective effect of areca inflorescence extract on hydrogen peroxide-induced oxidative damage to human serum albumin.
Cheng F, Chen W, Huang Y, Zhang C, Shen Y, Hai H, Zheng Y, Tang M, Zhao S, Liu J.
Food Res Int. 2011;44:98-102 

 
13. Reactive oxygen  species scavenging activity and DNA protecting effect of fresh  and naturally fermented coconut sap.
Chen W, Zhu Q, Xia Q, Cao W, Zhao S, Liu J.
J Food Biochem. 2011;35:1381-1388

 
14. Stimulation of GSH synthesis to prevent oxidative stress-induced apoptosis by hydroxytyrosol in human retinal pigment epithelial cells: Activation of Nrf2 and JNK-p62/SQSTM1 pathways.
Zou X, Feng Z, Li Y, Wang Y, Wertz K, Weber P, Chen Y and Liu J
J. Nutr Biochem 2012 Aug;23(8):994-1006. doi: 10.1016/j.jnutbio.2011.05.006. Epub 2011 Sep 19.

 
15. Enhanced autophagy plays a cardinal role in mitochondrial dysfunction in type 2 diabetic Goto-Kakizaki (GK) rats: Ameliorating effects of (–)-epigallocatechin-3-gallate.
Yan J, Feng Z, Liu J, Shen W, Wang Y, Wertz K, Weber P, Long J, and Liu J
J. Nutr Biochem 2012 Jul;23(7):716-24. doi: 10.1016/j.jnutbio.2011.03.014. Epub 2011 Aug 4.

 
16. Protective effects of mitochondrial nutrients on performance and mitochondrial function in exhaustively exercised rats.
Sun M, Qian F, Shen W, Tian C, Hao J, Sun L and Liu J
Scand J Med Sci Sports 2012 Dec;22(6):764-75. doi: 10.1111/j.1600-0838.2011.01314.x. Epub 2011 Apr21.

 
17.  Adenine sulfate improves cardiac function and the cardiac cholinergic system after myocardial infarction in rats. 
Sun L, Lu J, Yu XJ, Li DL, Xu XL, Wang B, Ren KY, Liu JK, Zang WJ
J Pharmacol Sci. 2011;115(2):205-13.  

 
 
2010:
 
1. Hydroxytyrosol promotes mitochondrial biogenesis and mitochondrial function in 3T3-L1 adipocytes.
Hao J, Shen W, Yu G, Jia H, Li X, Feng Z, Wang Y, Weber P, Wertz K, Sharman E, Liu J
J Nutr Biochem 21:634-644.2010. PDF

 
2. Mitochondrial decay is involved in BaP-induced cervical damage.
Gao M, Long J, Li Y, Shah W, Fu L, Liu J, and Wang Y
Free Radic Biol Med  49(11):1735-45), 2010. 

 
3. A novel system for in vivo neprilysin gene delivery using a syringe electrode.
 Li Y, Wang J, Liu J, Liu F.
J Neurosci Methods. 193(2):226-31, 2010. PDF

 
4. Cr(VI) induces mitochondrial-mediated and caspase-dependent apoptosis through reactive oxygen species-mediated p53 activation in JB6 Cl41 cells.
Son YO, Hitron JA, Wang X, Chang Q, Pan J, Zhang Z, Liu J, Wang S, Lee JC, Shi X Toxicol Appl Pharmacol. 245(2):226-35, 2010. PDF

 
5. Anti-Parkinsonism activity of high doses of B vitamins in a chronic cellular model and an α-synuclein transgenic Drosophila model.
Jia H, Liu Z., Li X., Feng Z., Hao J., Li X., Shen W, Zhang H., Gao H, and Liu J
Neurobiol. Aging 31(4):636-46,2010. PDF

 
6. Combination of R-a–Lipoic acid and acetyl-L-carnitine prevents mitochondrial dysfunction and oxidative damage in a rotenone-treated human neuroblastoma cellular model of Parkinson’s disease.
Zhang H, Jia H, Liu JH, ShenW, Ao N, Wang X, and Liu J
J. Cell. Mol. Med. 14:33-43, 2010. PDF

 
7. The polyhydroxylated fullerene derivative C60(OH)24 protects mice from ionizing radiation-induced immune and mitochondrial dysfunction.
Cai X, Hao J, Zhang X, Yu B, Ren J, Luo C, Li Q, Huang Q, Li W, Shi, X, and Liu J
Toxicol. Appl. Pharmacol. 243(1):27-34. 2010. PDF

 
8. Dietary amelioration of locomotor, neurotransmitter, and mitochondrial aging.
Aksenov V, Long J, Lokuge S, Foster JA, Liu J*, Rollo CD*
Exp. Biol. Med. 235:66-76, 2010. PDF

 
9. α-Tocopherol is an effective phase II enzyme inducer: Protective effects on acrolein-induced oxidative stress and mitochondrial dysfunction.
Feng Z, Liu Z, Li X, Jia H, Sun L, Tian C and Liu J
J. Nutr. Biochem. 21(12):1222-31, 2010. PDF

 
10. A milk-based wolfberry preparation prevents prenatal stress-induced cognitive impairment of offspring rats, and inhibits oxidative damage and mitochondrial dysfunction in vitro.
Feng Z, Jia H, Li X, Bai Z, Liu Z, Sun L, Zhu Z, Bucheli P, Ballèvre O, Wang J, Liu J. Neurochem Res. 21(11):1089-98, 2010. PDF

 
11. Hydroxytyrosol protects oxidative damage by simultaneous activation of mitochondrial biogenesis and phase II enzyme systems in retinal pigment epithelial cells.
Zhu L, Liu Z, Feng Z, Hao J, Shen W, Li X, Sun L, Sharman E, Wang Y, Wertz K, Weber P, Shi, X and Liu J
J. Nutr. Biochem. 21(11):1089-98, 2010. PDF

 
12. Endurance exercise causes mitochondrial and oxidative stress in rat liver: Effects of a combination of mitochondrial targeting nutrients.
Sun L, Shen W, Liu Z, Guan S, Liu J, Ding S
Life Sci. ;86(1-2):39-44, 2010. PDF

 
13. Anti-convulsant Effect and Mechanism of Astragalus mongholicus Extract In Vitro and In Vivo: Protection Against Oxidative Damage and Mitochondrial Dysfunction. 

Aldarmaa J, Liu Z, Long J, Mo X, Ma J, Liu J.
Neurochem Res. 35:33-41, 2010. PDF
 
14. Mechanism of DNA damage induced by arecaidine: The role of Cu (II) and alkaline conditions.
Chen W, Liu X, Shi J, Zheng Y, Zhao S and Liu J
Food Chem. 119 :433–436, 2010. PDF
 

 

 
2009:
 
1. Targeting mitochondrial biogenesis for preventing and treating insulin resistance in diabetes and obesity:  Hope from natural mitochondrial nutrients.
Liu J, Shen W,  Zhao B, Wang Y, Wertz K, Weber P, Zhang P
Adv. Drug Deliv. Rev. 61:1343-52, 2009. PDF

  
2. Grape Extract Protects Mitochondria from Oxidative Damage and Improves Locomotor Dysfunction and Extends Lifespan in a Drosophila Parkinson’s Disease Model.
Long J, Gao H, Sun L, X. Shi, Liu J*, Zhao-Wilson X*
Rejuv. Res. 12: 321-31, 2009. PDF
 
3. Comparison of two methods for assaying complex I activity in mitochondria isolated from rat liver, brain and heart.
Long J, Ma J, Luo C, Mo X, Sun L, Zang W, Liu J.
Life Sci. 85:276-80, 2009. PDF

  
4. Neuronal mitochondrial amelioration by feeding acetyl-L-carnitine and lipoic acid to aged rats.
Aliev, G, Liu, J,Shenk JC, Fischbach K, Pacheco GJ, Chen SG, Obrenovich ME, Ward WF, Richardson AG, Smith MA, Gasimov E, Perry G, Ames BN.
J. Cell. Mol. Med. 13:320-333, 2009. PDF

 
5. The effect of acetyl-L-carnitine and R-alpha-lipoic acid treatment in ApoE4 mouse as a model of human Alzheimer’s disease.
Shenk, J C., Liu, J., Fischbach, K., Xu, K., Puchowicz, M., Obrenovich, M. E., Gasimov, E., Alvarez, L. M., Ames, B. N., Lamanna, J. C., Aliev, G.
J Neurol Sci. 283(1-2):199-206, 2009. PDF

 
6. Mitochondrial decay in the brains of old rats: Ameliorating effect of alpha-lipoic acid and acetyl-L-carnitine. 
Long, J., Gao, F., Tong, L., Cotman, C. W., Ames, B. N., and Liu, J.
Neurochem Res. 34:755-63, 2009. PDF

 
7. Neuronal mitochondrial toxicity of malonaldehyde: Inhibitory effects on respiratory function and enzyme activities in rat brain mitochondria.
Long, J., Liu, C., Sun, L., Gao, H., and Liu, J.
Neurochem Res., 34:786-94, 2009. PDF

 
8. Akitane Mori, the Artistic Neurochemist. Neurochem.
Liu, J., and Hiramatsu, M.
 Res. 34:593-600, 2009. PDF
  
9. Mitochondrial nutrients improve immune dysfunction in the type 2 diabetic Goto-Kakizaki rats.
Hao, J., Shen, W., Ren, J., Tian, C., Li, X., Long, J., and Liu, J.
J. Cell. Mol. Med. 13, 701-11,2009. PDF
 
 

2008:
 
1. A combination of nutriments improves mitochondrial biogenesis and function in skeletal muscle of type 2 diabetic Goto–Kakizaki rats.
Shen, W., Hao, J., Tian, C., Ren, J., Yang, L., Li, X., Luo, C., Cotman, C. W., and Liu, J.
PLoS ONE 3(6):e2328, 2008. PDF

 
2. Polyhydroxylated fullerene derivative C60(OH)24 prevents mitochondrial dysfunction and oxidative damage in a MPP+-induced cellular model of Parkinson ’s disease.
Cai, X., Jia, H., Liu, Z., Hou, B., Luo, C., Feng, Z., Li, W., and Liu, J.
J. Neurosci. Res. 86:3622-3634., 2008. PDF

 
3. An improved spectrophotometric method for a more specific and accurate assay of mitochondrial complex III activity.
Luo, C., Long, J, and Liu, J.
Clin.Chim. Acta 395:38-41, 2008. PDF
  
4. High doses of nicotinamide prevent oxidative mitochondrial dysfunction in a cellular model and improves motor deficit in a Drosophila model of Parkinson’s disease J.
Jia, H., Li, X., Gao, H., Feng, Z., Li, X.S., Zhao, L., Jia, X., Zhang, H., Liu, J.
Neurosci. Res  86:2083-90, 2008. PDF
  
5. NF-kB regulates prenatal stress-induced cognitive impairment in offspring rats.
Li, H., Li, X., Jia, N., Cai, Q., Bai, Z., Chen R., Song, T., Zhu, Z., and Liu, J.
Behav. Neurosci. 122:331-339, 2008. PDF

 
6. Lipoamide protects retinal pigment epithelial cells from oxidative stress and mitochondrial dysfunction.
Li, X., Liu, Z., Luo, C., Jia, X., Sun, L., Hou, B., Shen, W., Packer, L., Cotman, C. W., and Liu, J.
Free Radic. Biol. Med. 44:1465-74, 2008. PDF
 
7. Protective effects of R-alpha-lipoic acid and acetyl-L-carnitine in MIN6 and isolated rat Islet cells chronically exposed to oleic acid.
Shen, W.,  Liu, K., Tian, C.,  Yang, L., Li, X., Packer, L., Head, E., and Liu, J.
J. Cell. Biochem. 104:1232-43., 2008.PDF
 
8. R-α-Lipoic acid and acetyl-L-carnitine complementarily promote mitochondrial biogenesis in 3T3-L1 adipocytes.
Shen, W., Liu, K., Tian, C., Yang, L., Li, X., Ren, J., Packer, L., Cotman, C. W., and Liu, J.
Diabetologia 51:165-174, 2008. PDF
 
9. The effects and mechanisms of mitochondrial nutrient α-lipoic acid on improving age-associated mitochondrial and cognitive dysfunction: an overview.
Liu, J.
Neurochem. Res. 33:194-203, 2008. PDF

 
10. Mitochondrial dysfunction enhances susceptibility to oxidative stress by down-regulation of thioredoxin in human neuroblastoma cells.
Ding, H., Gao, J., Zhu, Z. and Xiong, Y. and Liu, J.
Neurochem. Res.33:43-50, 2008.PDF

 


 
2007:
 
1. Hydroxytyrosol protects retinal pigment epithelial cells from acrolein-induced oxidative stress and mitochondrial dysfunction.
Liu, Z., Sun, L., Zhu, L., Jia, X., Li, X., Jia, H., Wang, Y., Weber, P., Long, J., and Liu, J.
J. Neurochem.103:2690-2700 2007.
  
2. Sex and region difference of the expression of ERK in prenatal stress offspring hippocampus.
Cai, Q., Zhu, Z., Huang, S., Li, H., Fan, X., Jia, N., Bai, Z., Song, L., Li, Q, and Liu, J.
Int. J. Dev. Neurosci. 25:207-213, 2007.


3. D-Galactose toxicity in mice is associated with mitochondrial dysfunction: Protecting effects of mitochondrial nutrient R-alpha-lipoic acid. 
Long, L., Wang, X., Gao, H., Liu, Z., Liu, C., Miao, M., Cui, X., Packer, L. and Liu, J.
Biogerontology 8:373-381, 2007.
 
4. Acrolein, a toxicant in cigarette smoke, causes oxidative damage and mitochondrial dysfunction in retinal pigment epithelial cells:Protection by (R)--lipoic acid.
Jia, L., Liu ,Z., Sun, L., Miller, S. S., Cotman, C. W., Ames, B. N., and Liu, J.
Invest. Ophthalmol. Vis. Sci. 48:339-348, 2007.
 
  

2006:
 
 1.An NADH-tetrazolium-coupled sensitive assay for malate dehydrogenase in mitochondria and crude tissue homogenates.
Luo C, Wang X, Long J, Liu J.
J Biochem Biophys Methods. 2006 Aug 31;68(2):101-11. Epub 2006 Apr 26.
PMID:16740313
 

2.Malonaldehyde acts as a mitochondrial toxin: Inhibitory effects on respiratory function and enzyme activities in isolated rat liver mitochondria.
Long J, Wang X, Gao H, Liu Z, Liu C, Miao M, Liu J.
Life Sci. 2006 Sep 5;79(15):1466-72. Epub 2006 May 7.
PMID:16737718
 
 3.Acrolein is a mitochondrial toxin: effects on respiratory function and enzyme activities in isolated rat liver mitochondria.
Sun L, Luo C, Long J, Wei D, Liu J.
Mitochondrion. 2006 Jun;6(3):136-42. Epub 2006 May 4.
PMID:16725382
 
 4.Chronic systemic D-galactose exposure induces memory loss, neurodegeneration, and oxidative damage in mice: protective effects of R-alpha-lipoic acid.
Cui X, Zuo P, Zhang Q, Li X, Hu Y, Long J, Packer L, Liu J.
J Neurosci Res. 2006 Aug 15;84(3):647-54.
PMID:16710848