基本信息

                                

     
      

李剑君,女,博士,教授,博导,西安交通大学生命科学与技术学院

办公地点:教二楼北(生命学院)521室  

办公电话:82664224

Email:jjunli@mail.xjtu.edu.cn

通信地址:西安交通大学生命科学与技术学院生物医学分析技术与仪器研究所(710049)

 

教育经历

1995年于西北大学本科毕业获化学工程与工艺工学学士学位
1999年硕士毕业于西北大学生物化学工程工学硕士学位
2003年获得西安交通大学生物医学工程工学博士学位
工作经历

 2004-2007,生物工程系,讲师;

 20077月-今,生物分析技术与仪器研究所,讲师,副教授,教授;

 2013-2014,美国伊利诺伊大学香槟分校化学系访问学者。

研究领域

    多形貌贵金属纳米颗粒的制备及光谱性质调控
    基于纳米金的生物光学探针制备及应用
    基于多信息融合的生物光谱传感
    生物化学反应与分析技术
    生物化学反应与分离工程

发表论文

2018

 

1.  Ting-Yang Xing, Jing Zhao, Guo-Jun Weng , Jian-Jun Li * , Jian Zhu, Jun-Wu Zhao*. Synthesis of dual-functional Ag/Au nanoparticles based on the decreased cavitating rate under alkaline conditions and the colorimetric detection of mercury(ii) and lead(ii), Journal of Materials Chemistry C, 2018, 6 (28), 7557-7567. (SCI1  影响因子:5.976)

2. Ying Qi, Jing Zhao, Guo-jun Weng, Jian-jun Li, Xin Li, Jian Zhu*, Jun-wu Zhao*. A Colorimetric/SERS Double-mode Sensor for Detection of Mercury (II) Based on Rhodanine Stabilized Gold Nanobipyramids, Journal of Materials Chemistry C, 2018, 6(45), 12283-12293. (SCI1  影响因子:5.976)

3.  Jian Zhu *, Bing-zheng Zhao, Ying Qi, Jian-Jun Li, Xin Li, Jun-Wu Zhao*. Colorimetric determination of Hg(II) by combining the etching and aggregation effect of cysteine-modified Au-Ag core-shell nanorods, Sensors & Actuators: B. Chemical, 2018, 255, 2927-2935. (SCI1  影响因子:5.667  ESI )

4.  Ying Qi, Jing Zhao, Guo-jun Weng, Jian-jun Li, Jian Zhu*, Junwu Zhao*. Modification-free colorimetric and visual detection of Hg2+ based on the etching from core-shell structural Au-Ag nanorods to nanorice, Sensors & Actuators: B. Chemical, 2018, 267, 181-190. (SCI1  影响因子:5.667)  

5.  Fan Zhang, Na Wu, Jian Zhu*, Jing Zhao, Guo-jun Weng, Jian-jun Li, Jun-wu Zhao*. Au@AuAg yolk-shell nanotriangles with controlled interior gap for the improved surface-enhanced Raman scattering of rhodamine 6G, Sensors & Actuators: B. Chemical, 2018, 271, 174-182. (SCI1  影响因子:5.667)

6.  Ying Qi, Ting-yang Xing, Jing Zhao, Guo-jun Weng, Jian-jun Li, Jian Zhu*, Jun-wu Zhao*. Tuning the surface enhanced Raman scattering performance of anisotropic Au core-Ag shell hetero-nanostructure: the effect of core geometry, Journal of Alloys and Compounds, 2019, 776, 934-947. (SCI:小类1  影响因子:3.779)  

7.  Jing Zhao, Guo-jun Weng, Jian-jun Li, Jian Zhu, Jun-wu Zhao*. Polyester-based nanoparticles for nucleic acid delivery, Materials Science and Engineering: C, 2018, 92, 983-994. (SCI2  影响因子:5.080)

 8.  Jian Zhu, Zai-jie Xu, Guo-jun Weng, Jing Zhao, Jian-jun Li, Jun-wu Zhao *. Etching-dependent fluorescence quenching of Ag-dielectric-Au three-layered nanoshells: the effect of inner Ag nanosphere, Spectrochimica Acta Part A, 2018, 200, 43-50. (SCI2  影响因子:2.880)

9. Jian Zhu*, Tian-tian Jia, Jian-jun Li, Xin Li, Jun-wu Zhao *. Plasmonic spectral determination of Hg(II) based on surface etching of Au-Ag Core-Shell Triangular Nanoplates: from spectrum peak to dip, Spectrochimica Acta Part A, 2019, 207, 337347. (SCI2  影响因子:2.880)

10.  Jian Zhu*, Xiao-hong Chen, Jian-jun Li, Jun-wu Zhao *. The synthesis of Ag-coated tetrapod gold nanostars and the improvement of surface-enhanced Raman scattering, Spectrochimica Acta Part A, 2019, 211, 154165. (SCI2  影响因子:2.880)

11. Si-nan Wang, Jian Zhu*, Xin Li, Jian-jun Li, Jun-wu Zhao *. Fluorescence turn-on sensing of trace cadmium ions based on EDTA-modified CdTe@CdS quantum dot, Spectrochimica Acta Part A, 2018, 201, 119-127. (SCI2  影响因子:2.880) 

12. Jian Zhu*, Hui Chang, Jian-jun Li, Jun-wu Zhao *. Using silicon-coated gold nanoparticles to enhance the fluorescence of CdTe quantum dot and improve the sensing ability of mercury (II), Spectrochimica Acta Part A, 2018, 188, 170-178. (SCI2  影响因子:2.880)

13. Jian Zhu*, Mei-jin Liu, Jian-jun Li, Xin Li, Jun-wu Zhao *. Multi-branched gold nanostars with fractal structure for SERS detection of the pesticide thiram, Spectrochimica Acta Part A, 2018, 189, 586-593. (SCI2  影响因子:2.880)

14. Jian Zhu*, Xin Li, Jian-jun Li, Jun-wu Zhao *. Enlarge the biologic coating-induced absorbance enhancement of Au-Ag bimetallic nanoshells by tuning the metal composition, Spectrochimica Acta Part A, 2018, 189, 571-577. (SCI2  影响因子:2.880)

15. Jian-Jun Li, Chen Wu, Jing Zhao, Guo-jun Weng, Jian Zhu, Jun-wu Zhao *. Synthesis and SERS activity of super-multibranched AuAg nanostructure via silver coating-induced aggregation of nanostars, Spectrochimica Acta Part A, 2018, 204, 380-387. (SCI2  影响因子:2.880)

16. Jian Zhu*, Na Wu, Fan Zhang, Xin Li, Jian-jun Li, Jun-wu Zhao *. SERS detection of 4-Aminobenzenethiol based on Au- Ag alloy triangular nanoframe with sandwich structure, Spectrochimica Acta Part A, 2018, 204, 754-762. (SCI2  影响因子:2.880)

17. Jian Zhu, Si-nan Wang, Jian-jun Li, Jun-wu Zhao *. The effect of core size on the fluorescence emission properties of CdTe@CdS core@shell quantum dots, Journal of Luminescence, 2018, 199, 216-224. (SCI2  影响因子:2.732)

18. Jian-jun Li, Tao Li, Jian Zhu, Jun-wu Zhao*. Reversible Tuning the Aspect Ratio and Plasmonic Shift of Gold Nanorods in Alkaline Environment: Growth, Etching and Rebuilding, Plasmonics, 2018, 13, 14331439. (SCI3  影响因子:2.366) 

19. Guo-jun Weng, Xiao-jing Dong, Jing Zhao, Jian-jun Li, Jian Zhu, Jun-wu Zhao*. Selective oxidative etching of CTAC-stabilized multi-branched gold nanoparticles: application in spectral sensing of iodide ions, J Nanopart Res, 2018, 20(9), 256. (SCI3  影响因子:2.127)

20. Guo-jun Weng, YueYang, Jing Zhao, Jian Zhu, Jian-jun Li*, Jun-wu Zhao *. Preparation and SERS performance of Au NP/paper strips based on inkjet printing and seed mediated growth: The effect of silver ions, Solid State Communications, 2018, 272, 67-73. (SCI3  影响因子:1.549)

21. 杨玥, 翁国军, 赵婧, 李剑君*, 朱键, 赵军武. 纸质表面增强拉曼散射基底的制备及其应用进展[J]. 中国激光, 2018, 45(3), 307011-1.

22. 王司南,朱键,李剑君,赵军武. 基于CdTe QDs Au NPs内滤效应构建荧光“turn-on”模型检测精氨酸, 2018中国生物医学工程联合学术年会, 2018.09.20.

 

2017

1. Jian-Jun Li, Tao Li, Jian Zhu, Jun-Wu Zhao*, Reversible Tuning the Aspect Ratio and Plasmonic Shift of Gold Nanorods in Alkaline Environment: Growth, Etching and Rebuilding, Plasmonics, 2017, 1-7

2. Jing Zhao, Guorui Jin*, Guojun Weng, Jianjun Li, Jian Zhu, Junwu Zhao*, Recent advances in activatable fluorescence imaging probes for tumor imaging, Drug Discovery

Today, 2017, 22: 1367-1374. IDS: FK3JC; SCI; IF:6.369

3. Jian Zhu*, Hui Chang, Jian-Jun Li, Li Xin, Jun-Wu Zhao*, Dual-mode melamine detection based on gold nanoparticles aggregation-induced fluorescence “turn-on” and “turn-off” of CdTe quantum dots, Sensors & Actuators B-Chemical, 2017, 239: 906-915. (IDS:ED6FK; SCI; IF: 5.401 )

4. Ying Qi, Jian Zhu*, Jian-Jun Li, Jun-Wu Zhao*, Multi-mode iodide optical detection based on the etching of silver-coated gold nanobipyramid, Sensors & Actuators B-Chemical, 2017, 253: 612–620. (IDS: FH4LG; SCI; IF: 5.401)

5. Jian Zhu *, Bing-zheng Zhao, Ying Qi, Jian-Jun Li, Xin Li, Jun-Wu Zhao*, Colorimetric determination of Hg(II) by combining the etching and aggregation effect of cysteine-modified Au-Ag core-shell nanorodsSensors & Actuators B-Chemical, 2017, 255 : 2927-2935. (IDS: FM0VU; SCI; IF: 5.401)

6. Cuiping Yao, Jing Wang,  Aixian Zheng, Lingjie Wu, Xiaolong Zhang , Xiaolong Liu, A fluorescence sensing platform with the MnO2 nanosheets as an effective oxidant for glutathione detection, Sensors & Actuators B-Chemical, 2017, 252:

30-36.  IDS: FE5UT; SCI: IF: 5.401

7. Jing Zhao, Li Long, Guojun Weng, Jianjun Li, Jian Zhu * and Jun-Wu Zhao*, Multi-branch Au/Ag bimetallic core–shell–satellite nanoparticles as a versatile SERS substrate: the effect of Au branches in a mesoporous silica interlayer, Journal of Materials Chemistry C, 2017, 5: 12678 – 12687.IDS : FQ0TN; SCI; IF: 5.256

8. Yang Zhe, Sun Na., Zhao Chenyang, Liu Jie and Tian Zhongmin *. Hybrid nanoparticles coated with hyaluronic acid lipoid for targeted co-delivery of paclitaxel and curcumin to synergistically eliminate breast cancer stem cells , Journal of Materials Chemistry B, 2017, 5: 6762-6775.IDS:FE5SB; SCI; IF: 4.543

9. Jian Zhu*, Zhu-Jun Zhao, Jian-Jun Li, Jun-Wu Zhao*Fluorescent detection of ascorbic acid based on the emission wavelength shift of CdTe quantum dots, Journal of Luminescence, 2017, 192: 47–55. ( IDS:FJ8RX; SCI; IF:2.686 )

10. Jian Zhu, Zhu-Jun Zhao, Jian-Jun Li, Jun-Wu Zhao*, CdTe quantum dot-based fluorescent probes for selective detection of Hg (II): the effect of particle size, Spectrochimica Acta Part A-Molecular and Biomolecular Spectroscopy, 2017, 177: 140–146. ( IDS:EP0KP; SCI; IF: 2.536)

11. Jian Zhu*, Hui Chang, Jian-Jun Li, Jun-Wu Zhao*, Using silicon-coated gold nanoparticles to enhance the fluorescence of CdTe quantum dot and improve the sensing ability of mercury (II), Spectrochimica Acta Part A, 2018, 188 : 170–178. ( IDS:FJ3CR; SCI; IF: 2.536)

12. Jian Zhu*, Mei-Jin Liu, Jian-Jun Li, Xin Li, Jun-Wu Zhao*, Multi-branched gold nanostars with fractal structure for SERS detection of the pesticide thiram, Spectrochimica Acta Part A, 2018, 189: 586-593. (IDS:FK6IJ; SCI; IF:2.536)

13. Jian Zhu*, Xin Li, Jian-jun Li, Jun-wu Zhao*, Enlarge the biologic coating-induced absorbance enhancement of Au-Ag bimetallic nanoshells by tuning the metal composition, Spectrochimica Acta Part A, 2017, 189: 571-577. (IDS:FK6IJ; SCI; IF:2.536 ) 

14. Chun-Hong Zhang, Jian Zhu, Jian-Jun Li*, and Jun-Wu Zhao*, Small and Sharp Triangular Silver Nanoplates Synthesized Utilizing Tiny Triangular Nuclei and Their Excellent SERS Activity for Selective Detection of Thiram Residue in Soil, ACS Applied Materials &Interfaces, 2017, 9: 17387−17398. (IDS: EW4VI; SCI; IF: 7.504 )

15. Jian Zhu*, Qi Zhang, Chun-hong Zhang, Guo-jun Weng, Jing Zhao, Jian-jun Li, Jun-wu Zhao*, Synthesis of colloidal gold nanobones with tunable negative  curvatures at end surface and their application in SERS, Journal of Nanoparticle Research, 2017, 19(11): 36401-36413.  

16. Jian Zhu*, Mei-Jin Liu, Jian-Jun Li, Xin Li, Jun-Wu Zhao*, Synthesis of gold nanostars with fractal structure: the application in surface-enhanced Raman scattering, European Physical Journal B, 2017, 90(11):21601-21608. 

17.李新,李剑君,朱键*,赵军武光纤光谱仪实时监测胶体金生长及凝聚实验室研究与探索. 2017, 36(12). 6-9.

 

    2016

1.    Li Jianjun, An Huiqin, Zhu Jian, Zhao Junwu *, Detecting glucose by using the Raman scattering of oxidized ascorbic acid: The effect of graphene oxide-gold nanorod hybridSensors & Actuators B: Chemical, 2016, 235:663-669

2.    Li Jianjun, Zhang Ning, Wang Jingyuan, Yang Chunyu, Zhu Jian, Zhao Junwu *. Tuning the EDTA induced self-assembly and plasmonic spectral properties of gold nanorods: application in surface-enhanced Raman scattering. Journal of Nanoparticle Research, 2016,18(2):18- 39

3.    Weng Guojun, Li Jianjun, Zhao Junwu *. Composition controlling the number of absorption peaks in three-layered metal-dielectric-metal nanoshell. Optoelectronics and Advanced Materials-Rapid Communications, 2016,10(3-4): 185-190

4.    Fan Zhang, Jian Zhu*, Hui-Qin An, Jian-Jun Li and Jun-Wu Zhao, A two-step approach to realize size- and shape-selective separation of crude gold nanotriangles with high purification, Journal of Materials Chemistry C, 2016,4: 568-580

5.    Jian Zhu*, Jing-Fei Wang, Jian-Jun Li, Jun-Wu Zhao*, Specific detection of carcinoembryonic antigen based on fluorescence quenching of Au-Ag core-shell nanotriangle probe, Sensors & Actuators: B. Chemical. 2016,233: 214–222

6.    Jian Zhu, Jing-Fei Wang, Jian-Jun Li, Jun-Wu Zhao*, Tuning The Fluorescence Quenching Properties Of Plasmonic Ag-Coated-Au Triangular Nanoplates: Application In Ultrasensitive Detection Of CEA, Plasmonics, 2016,11:565-572

7.    Jian Zhu, Yun-qi Yu, Jian-Jun Li, Jun-Wu Zhao*, Colorimetric detection of lead (II) ions based on accelerating surface etching of gold nanorods to nanospheres induced by sodium thiosulfate, RSC Adv., 2016, 6, 25611–25619 

8.    Jian Zhu, Jie Gao, Jian-Jun Li, Xin Li, Jun-Wu Zhao*, Improve the plasmonic spectral detection of alpha-fetoprotein: the effect of branch length on the coagulation of gold nanostars, Plasmonics, 2016,11:1175-1182

9.    Guojun Weng, Xiaojing Dong, Jian-Jun Li, Jun-Wu Zhao*, Halide ions can trigger the oxidative etching of gold nanorods with the iodide ions being the most efficient, Journal of Materials Science, 2016, 51(16): 7678-7690

10.Chun-hong Zhang, Jian Zhu, Jian-jun Li, Jun-wu Zhao*, Focus and enlarge the enhancement region of local electric field by overlapping Ag triangular nanoplates, The European Physical Journal Applied Physics, 2016, 73: 10501

11. Jian Zhu*, Beibei Chen, Fan Zhang, Jianjun Li, Junwu Zhao*, Ultra-Sensitive Detection Of AFP Based On Multi-Spectral Information From Face-To-Face Aggregation Of Gold Triangular Nanoplates, Journal Of Nanoscience And Nanotechnology, 2016,16:6854-6859 

12.Ying Qi, Jian Zhu, Jian-Jun Li, Jun-Wu Zhao*, Highly Improved Synthesis Of Gold Nanobipyramids By Tuning The Concentration Of Hydrochloric Acid, Journal Of Nanoparticle Research, 2016, 18:190

13.Ting-Yang Xing, Jian Zhu, Jian-Jun Li, Jun-Wu Zhao*, Morphology Modification Of Gold Nanoparticles From Nanoshell To C-Shape:Improved Surface Enhanced Raman Scattering, Journal Of Applied Physics, 2016, 119: 243104

 

 

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