Office: Room 107s Jiao-Er Building, Xian Jiaotong University, Beilin District, Xi’an, 710049, China

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1.      Super-broadband ultrasound perfusion imaging of deep microvascular and single bubble within the vascular, 2008-2010, National Nature Science Foundation of China (No. 10704060).

2.      Study on the methods of building local plaque animal modal based on ultrasound cavitation endothelium damage, 2013, National Nature Science Foundation of China (No. 31271003)

3.      Atherosclerosis animal model based on controlled ultrasound cavitation endothelial injury and its in vivo evaluation, 2015-2018, National Nature Science Foundation of China (No. 31470909)




1.      Noninvasive and high resolution ultrasound functional and molecular quantitative imaging of vulnerable plaque, National Basic Research Program 973 (No. 2010CB732603) from Ministry of Science and Technology, 2010-2014

2.      Drug-carried microparticles or Microbubbles, Locallized Controlled Release by Low Intensity Focused Ultrasound (LIFU) and Real-time Monitoring Imaging, State Key Program of National Natural Science of China (No. 30630024).


2006        Ph.D. in Biomedical Engineering

                Dept. Biomedical Engineering, School of Life Science and Technology, Xian Jiaotong University, China

2000        M.S. in Material Engineering

                School of Materials Science & Engineering, Xian Jiaotong University, China

1995        B.S. in Chemical Engineering

                  Dept. Chemical Engineering, Qingdao University of Science and Technology 

Research Experience

2006-08   Research assistant, Dept. Biomedical Engineering, School of Life Science and Technology, Xian Jiaotong University

2008-14   Associate Professor,  Dept. Biomedical Engineering, School of Life Science and Technology, Xian Jiaotong University

2015-16  Visiting Scholar, Center of Medical and Industrial Ultrasound, Applied Physics Laboratory, University of Washinton, Seattle

2016-   Associate Professor,  Dept. Biomedical Engineering, School of Life Science and Technology, Xian Jiaotong University



1. Mingxi Wan, Yujin Zong, Supin Wang, Biomedical Ultrasound, Science Press, Beijing, 2010
2. Mingxi Wan, Yujin Zong, Supin Wang, Mingzhu Lu, Experiments in Biomedical Ultrasound, XI'AN Jiaotong University Press, Xi'an, 2010
3. Yujin Zong, Shanshan Xu, Tom Matula, Mingxi Wan, Chapter 5. Cavitation-enhanced mechanical effects and applications, in book: Cavitation in Biomedicine, Principles and Techniques, Editor: M.Wan, Y. Feng, Gail ter Haar, Springer, 2015
REFERRED JOURNAL ARTICLES:                                   
1.   Shanshan Xu, Nan Chang, Rui Wang, Xiaodong Liu, Shifang Guo, Wupin Wang, Yujin Zong*, Mingxi Wan*,Acoustic droplet vaporization and inertial cavitation thresholds andefficiencies of nanodroplets emulsions inside the focused region using adual-frequency ring focused ultrasound, Ultrasonics Sonochemistry, 2018, 48: 532-537
2.   Chen Bai, Meiling Ji, Xinyu Zhang, Yujin Zong*, Mingxi Wan*, Design and Characterization of an Acoustically and Structurally Matched 3-D-Printed Model for Transcranial Ultrasound Imaging, IEEE Trans on UFFC, 2018, 65(5):
3.   Shukuan Lu, Hong Hu, Xianbo Yu, Jiangying Long, Bowen Jing, Yujin Zong*, Mingxi Wan*, Passive acoustic mapping of cavitation using eigenspace-based robust Capon beamformer in ultrasound therapy, Ultrasonics Sonochemistry, 2018, 41: 670-679
4.   Diya Wang, Mengnan Xiao, Hong Hu, Yu Zhang, Zhe Su, Shanshan Xu, Yujin Zong, Mingxi Wan, DCEUS-based focal parametric perfusion imaging of microvessel with single-pixel resolution and high contrast, Ultrasonics, 2018, 84: 392-403
5.   Shifang Guo, Aiwei Shi, Shanshan Xu, Xuan Du, Xin Wang, Yujin Zong, Ayache Bouakaz, and Mingxi Wan, Lowering of acoustic droplet vaporization threshold via aggregation, Appl. Phys. Lett., 2017, 111: 254102
6.   Diya Wang, Yujin Zong, Xuan Yang, Hong Hu, Jinjin Wan, Lei Zhang, Ayache Bouakaz, Mingxi Wan, Ultrasound Contrast Plane Wave Imaging Based on Bubble Wavelet Transform: in vitro and in vivo Validations, Ultrasound in Medicine & Biology, 2016,  42(7): 1584-1597
7.   J. Hu#, Y. Zong#, J. Li, X. Zhou, J. Zhang, T. Zhu, M. Jiao, H. Su*, B. Bo, InVitro and In Vivo Evaluation of Targeted Sunitinib-Loaded Polymer Microbubbles against Proliferation of Renal Cell Carcinoma, Journal of Ultrasound in Medicine, 2016, 35: 589-597.
8.    A. Shi, P. Huang, S. Guo, L. Zhao, J. Jia, Y. Zong*, M. Wan*, Precise spatial control of cavitation erosion in a vessel phantom by using an ultrasonic standing wave, Ultrasonics Sonochemistry, 2016, 31: 163-172.
9.   J. Tan, B. Pham, Y. Zong, C. Perez, D. Maris, A. Hemphill, C. Miao, T. Matula, P. Mourad, H. Wei, D. Sellers, P. Horner*, S. Pun*, Microbubbles and Ultrasound Increase Intraventricular Polyplex Gene Transfer to the Brain, Journal of Controlled Release, 2016, 231:86-93.
10.    Yangzi Qiao, Yujin Zong, Hui Yin, Nan Chang, Zhaopeng Li and Mingxi Wan, Spatial and temporal observation of phase-shift nano-emulsions assisted cavitation and ablation during focused ultrasound exposure, Ultrasonics Sonochemistry,2014, 21(5): 1745-1751
11.    Shanshan Xu, Yujin Zong, Wusong Li, Siyuan Zhang and Mingxi Wan, Estimation of bubble size distribution in acoustic droplet vaporization, Ultrasonics Sonochemistry, 2014, 21(3): 975-983
12.    Xiaolin Gu, Min Wei, Yujin Zong, Hujie Jiang, Mingxi Wan, Flow Quantification with Nakagami Parametric Imaging for Suppressing Contrast Microbubbles Attenuation, Ultrasound in Medicine & Biology, 2013, 39(4): 660–669
13.    Siyuan Zhang, Yujin Zong, Mingxi Wan, Xiaojun Yu, Quanyou Fu, Ting Ding, Fanyu Zhou, and Supin Wang, Compare ultrasound-mediated heating and cavitation between flowing polymer- and lipid-shelled microbubbles during focused ultrasound exposures, J. Acoust. Soc. Am. 2012, 131 (6): 4845-4855
14.    Yiyang Wan, Siyuan Zhang, Yujin Zong and Mingxi Wan, Formation of two-way Lamb waves and force potential wells using single conventional ultrasonic transducer, Proceedings of Meetings on Acoustics, 2012, Vol. 15, 045003
15.   Zhong Hui, Ding Guanhua, She Yanmin, Y. Zong, M. Wan*, “The study of sub-harmoniccavitation maging based on pulse inversion technique for the monitoring of high intensity focused ultrasound therapies,” Journal of Medical Imaging and Health Informatics, vol. 4, pp. 410-415, 2014.
16.    Zong Yujin, Wan Mingxi, The Study of Sub-Harmonic Cavitation Imaging Based on Pulse Inversion Technique for the Monitoring of High Intensity Focused Ultrasound Therapies, Journal of medical imaging and health informatics, 2014, 4(3): 410-415
17. Haili Su, Yongfeng Du, Yunqiu Qian, Yujin Zong, Jun Li, Ran Zhuang, Jianguo He, Zhangrui Wei, Jun Zhang, Xiaodong Zhou, Targeted Ultrasound Contrast Imaging of Matrix Metalloproteinase-2 in Ischemia–Reperfusion Rat Model: Ex Vivo and In Vivo Studies, Molecular Imaging and Biology, 2011, 13(2): 293-302
18.    Zong YJ, Wan MX, Wang SP, Zhang GL. Optimal design and experimental investigation of surfactant encapsulated microbubbles. Ultrasonics. 2006, 44(S1): e119-e122.
19.    Zong YJ, Li B, Wan MX. Detection of individual microbubbles using wavelet transform based on a theoretical bubble oscillation model. Lecture Notes in Computer Science. 2006, 4222: 354-363.
20.    Zong YJ, Wan MX, Wang SP, Chen H, Zhang G. Optimal design and experimental measurement of the subharmonic characterizations of encapsulate microbubble. Chinese Journal of Acoustics. 2006, 25(1): 45-57.
1.     Y. Zong, R. Wang, X. Zou, L. Zhang, G. Liu, and M. Wan*, “Local cavitation induced vessel wall injury of artery and its potential application in animal model of atherosclerosis,” IEEE International Ultrasonics Symposium, Taipei, Oct. 21-24, 2015.
2.     Y. Zong, X. Zou, R. Wang, Y. Feng, M. Wan*, Ultrasound-enhanced extravasation of multifunctional nanodroplets from leaky vessel, IEEE Ultrasonics Symposium (IUS), IEEE International Ultrasonics Symposium, Taipei, Oct. 21-24, 2015
3.     Y.J. Zong, J.J. Wan, MX. Wan. (2014) Non-invasive assessment of mechanical and hemodynamic parameters of carotid artery and plaque, International conference on biomedical ultrasound, (Shenzhen)
4.     YJ. Zong, N. Zheng, SS Xu, MX. Wan. (2013) Low intensity focused ultrasound triggered local drug delivery from liposome-loaded microbubbles, International Society for Therapeutic Ultrasound Symposium (Shanghai)
5.     Mingxi Wan, Yujin Zong, (2012) Noninvasive Ultrasound Elastography and Contrast-Enhanced Parametric Imaging of Carotid Plaque, IEEE-EMBS International Conference on Biomedical and Health Informatics (Shenzhen)
6.     Y.J. Zong, J.J. Wan, Y.Z. Qiao, W.S. Li, X.R. Zou and M.X. Wan. (2013) Cavitation endothelium damage of large artery vessel: a potential application to animal model of atherosclerosis, International Conference on Health Informatics (Vilamoura)
7.   Jinjin Wan, Yujin Zong, Mimi Hu and Mingxi Wan, (2013)Noninvasive Strain Imaging and Hemodynamic Evaluation of Atherosclerosis, International Conference on Health Informatics (Vilamoura)
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